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Cerebral Vasculopathy in Neurofibromatosis Type 1: An Under-Recognized Problem?
Neurofibromatosis type 1 (NF1) is a common genetic disorder caused by mutations in the NF1 gene, which encodes neurofibromin, a GTPase-activating protein (GAP)-related domain that negatively regulates the Ras/mitogen-activated protein kinase (RAS/MAPK) signaling pathway.
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Advancing the Care of Children with Cerebrovascular Disease
Pediatric cerebrovascular disease is a significant cause of global morbidity and mortality among children.
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Advances In Craniosynostosis Repair
Innovations in craniosynostosis management and cranial vault remodeling have improved diagnosis, preoperative planning and treatment resulting in improved patient outcomes and more personalized care...
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BPD: Progress Through Teamwork and the National BPD Collaborative
Bronchopulmonary dysplasia (BPD) is the most common respiratory complication of prematurity, affecting an estimated 10,000 to 15,000 babies in the U.S. annually - about 33 percent of babies born with a birthweight of less than 1,000 grams.
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Addressing the Complexity of Cerebral Palsy Care
At the Barrow Neurological Institute at Phoenix Children’s, the research group of pediatric movement disorders neurologist, Dr. Michael Kruer, is leading efforts to better capture individual differences in CP through multi-dimensional phenotyping.